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Anecdote.

I had undiagnosed Familial Mediterranean Fever for years in my early 20s. Terrible, sickening abdominal inflammation attacks every few weeks.

After about 5 years I was desperate and one doctor said my gallbladder did show signs of low functioning, and recommended taking it out.

I did go into “remission” for about 8 months after. It eventually came back, but then faded soon after. It wasn’t until a few years later with a DNA test that I found the cause.

But I did always wonder if the surgery, along with my desperate hope to be better / not be wrong, had such a strong placebo effect that it actually did help me out.



> Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder... an autoinflammatory disease caused by mutations in Mediterranean fever gene, which encodes a 781–amino acid protein called pyrin.

https://en.wikipedia.org/wiki/Familial_Mediterranean_fever




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